Outbreak among healthy newborns due to a new variant of USA300-related meticillin-resistant Staphylococcus aureus.
J Hosp Infect
; 87(3): 145-51, 2014 Jul.
Article
em En
| MEDLINE
| ID: mdl-24856113
ABSTRACT
BACKGROUND:
The prevalence of community-associated meticillin-resistant Staphylococcus aureus (CA-MRSA) is increasing throughout the world and is an important cause of skin and soft tissue infection (SSTI) in children and neonates.AIM:
To describe the successful control of an outbreak caused by a new strain of CA-MRSA in a newborn nursery.METHODS:
The investigation of the outbreak in July 2012 is reported with the control measures taken. Molecular typing of the MRSA isolates was performed.FINDINGS:
An outbreak of SSTI caused by CA-MRSA occurred in a newborn nursery. Six neonates were infected in a one-month period [infection rate 8.5% (6/71)]. A new variant of CA-MRSA was responsible, which was characterized as USA300-related, Panton-Valentine Leucocidin (PVL) positive, arginine catabolic mobile element (ACME) negative, sequence type 8 (ST8), staphylococcal cassette chromosome mec (SCCmec) type IVa, agr type I and spa type t008. The outbreak among term neonates followed a rapid transmission pattern and was successfully controlled by implementing various outbreak control measures, including universal chlorhexidine bathing.CONCLUSION:
This is the first report of a hospital outbreak caused by a USA300-related CA-MRSA clone in Korea. Early recognition and reinforcement of infection control measures are important in decreasing transmission of CA-MRSA in a hospital setting.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Infecções Estafilocócicas
/
Infecção Hospitalar
/
Surtos de Doenças
/
Staphylococcus aureus Resistente à Meticilina
Tipo de estudo:
Risk_factors_studies
Limite:
Humans
/
Newborn
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Hosp Infect
Ano de publicação:
2014
Tipo de documento:
Article