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Liver-specific transcriptional modules identified by genome-wide in silico analysis enable efficient gene therapy in mice and non-human primates.
Chuah, Marinee K; Petrus, Inge; De Bleser, Pieter; Le Guiner, Caroline; Gernoux, Gwladys; Adjali, Oumeya; Nair, Nisha; Willems, Jessica; Evens, Hanneke; Rincon, Melvin Y; Matrai, Janka; Di Matteo, Mario; Samara-Kuko, Ermira; Yan, Bing; Acosta-Sanchez, Abel; Meliani, Amine; Cherel, Ghislaine; Blouin, Véronique; Christophe, Olivier; Moullier, Philippe; Mingozzi, Federico; VandenDriessche, Thierry.
Afiliação
  • Chuah MK; 1] Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium [2] Department of Cardiovascular Sciences, Center for Molecular & Vascular Biology, University of Leuven, Leuven, Belgium.
  • Petrus I; Department of Cardiovascular Sciences, Center for Molecular & Vascular Biology, University of Leuven, Leuven, Belgium.
  • De Bleser P; Department for Molecular Biomedical Research (DMBR), VIB - Ghent University, Ghent, Belgium.
  • Le Guiner C; 1] INSERM UMR 1089, Atlantic Gene Therapies, Université de Nantes, Nantes, France [2] CHU de Nantes, Nantes, France.
  • Gernoux G; 1] INSERM UMR 1089, Atlantic Gene Therapies, Université de Nantes, Nantes, France [2] CHU de Nantes, Nantes, France.
  • Adjali O; 1] INSERM UMR 1089, Atlantic Gene Therapies, Université de Nantes, Nantes, France [2] CHU de Nantes, Nantes, France.
  • Nair N; Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium.
  • Willems J; Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium.
  • Evens H; Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium.
  • Rincon MY; 1] Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium [2] Department of Cardiovascular Sciences, Center for Molecular & Vascular Biology, University of Leuven, Leuven, Belgium.
  • Matrai J; 1] Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium [2] Vesalius Research Center, VIB, Leuven, Belgium [3] University of Leuven, Leuven, Belgium.
  • Di Matteo M; 1] Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium [2] Department of Cardiovascular Sciences, Center for Molecular & Vascular Biology, University of Leuven, Leuven, Belgium.
  • Samara-Kuko E; Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium.
  • Yan B; 1] Vesalius Research Center, VIB, Leuven, Belgium [2] University of Leuven, Leuven, Belgium.
  • Acosta-Sanchez A; 1] Vesalius Research Center, VIB, Leuven, Belgium [2] University of Leuven, Leuven, Belgium.
  • Meliani A; 1] Genethon, Evry, France [2] University Pierre and Marie Curie, Paris, France.
  • Cherel G; 1] INSERM, U770, Le Kremlin Bicêtre, France [2] Université Paris-Sud, Le Kremlin Bicêtre, France.
  • Blouin V; 1] INSERM UMR 1089, Atlantic Gene Therapies, Université de Nantes, Nantes, France [2] CHU de Nantes, Nantes, France.
  • Christophe O; 1] INSERM, U770, Le Kremlin Bicêtre, France [2] Université Paris-Sud, Le Kremlin Bicêtre, France.
  • Moullier P; 1] INSERM UMR 1089, Atlantic Gene Therapies, Université de Nantes, Nantes, France [2] CHU de Nantes, Nantes, France.
  • Mingozzi F; 1] Genethon, Evry, France [2] University Pierre and Marie Curie, Paris, France.
  • VandenDriessche T; 1] Department of Gene Therapy & Regenerative Medicine, Free University of Brussels (VUB), Brussels, Belgium [2] Department of Cardiovascular Sciences, Center for Molecular & Vascular Biology, University of Leuven, Leuven, Belgium.
Mol Ther ; 22(9): 1605-13, 2014 Sep.
Article em En | MEDLINE | ID: mdl-24954473
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Sítios de Ligação / Dependovirus / Biologia Computacional / Fígado / Macaca Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Sítios de Ligação / Dependovirus / Biologia Computacional / Fígado / Macaca Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Bélgica País de publicação: Estados Unidos