Differences in response of acetylcholinesterase to diisopropylfluorophosphate in the mesencephalic raphe region. A microelectrophoretic, histochemical, and biochemical study in albino rats.
Acta Histochem
; 85(1): 65-72, 1989.
Article
em En
| MEDLINE
| ID: mdl-2496574
ABSTRACT
To demonstrate the DFP-effects on the AChE of the mesencephalic raphe region albino rats were investigated using the pharmaco-histochemical method of Butcher et al. (1975). At several times after 1 mg DFP/kg body weight, the histochemical reactions in certain AChE-containing neurons were measured semiquantitatively and compared with biochemical data. Additionally, the multiple forms of water-soluble AChE were separated by microelectrophoresis. Only the electrophoretical results indicate changes of the structural AChE composition 5 d after DFP administration.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Acetilcolinesterase
/
Núcleos da Rafe
/
Isoflurofato
/
Neurônios
Limite:
Animals
Idioma:
En
Revista:
Acta Histochem
Ano de publicação:
1989
Tipo de documento:
Article