A high-throughput robotic sample preparation system and HPLC-MS/MS for measuring urinary anatabine, anabasine, nicotine and major nicotine metabolites.

Wei, Binnian; Feng, June; Rehmani, Imran J; Miller, Sharyn; McGuffey, James E; Blount, Benjamin C; Wang, Lanqing

Wei, Binnian; Feng, June; Rehmani, Imran J; Miller, Sharyn; McGuffey, James E; Blount, Benjamin C; Wang, Lanqing.

Afiliação

Wei B; Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: bwei@cdc.gov.
Feng J; Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States. Electronic address: czf2@cdc.gov.
Rehmani IJ; Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Miller S; Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States.
McGuffey JE; Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Blount BC; Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States.
Wang L; Tobacco and Volatiles Branch, Division of Laboratory Sciences, National Center for Environmental Health, Centers for Disease Control and Prevention, Atlanta, GA, United States.

Clin Chim Acta ; 436: 290-7, 2014 Sep 25.

Article em En | MEDLINE | ID: mdl-24968308

Assuntos

Métodos Analíticos de Preparação de Amostras/métodos; Cromatografia Líquida de Alta Pressão/métodos; Nicotina/metabolismo; Nicotina/urina; Robótica; Espectrometria de Massas em Tandem/métodos; Urinálise/métodos; Alcaloides/metabolismo; Alcaloides/urina; Anabasina/metabolismo; Anabasina/urina; Métodos Analíticos de Preparação de Amostras/instrumentação; Animais; Criopreservação; Escherichia coli/enzimologia; Glucuronidase/metabolismo; Caracois Helix/enzimologia; Humanos; Hidrólise; Limite de Detecção; Piridinas/metabolismo; Piridinas/urina; Fumar/urina; Temperatura

Palavras-chave

Biomarker; Biomonitoring; High-throughput; Robotic; Tobacco exposure; Urinary metabolites

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Robótica / Cromatografia Líquida de Alta Pressão / Urinálise / Espectrometria de Massas em Tandem / Métodos Analíticos de Preparação de Amostras / Nicotina Limite: Animals / Humans Idioma: En Revista: Clin Chim Acta Ano de publicação: 2014 Tipo de documento: Article País de publicação: Holanda

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