High-resolution structure of a virally encoded DNA-translocating conduit and the mechanism of DNA penetration.
J Virol
; 88(18): 10276-9, 2014 Sep.
Article
em En
| MEDLINE
| ID: mdl-24990998
ABSTRACT
Although ÏX174 DNA pilot protein H is monomeric during procapsid assembly, it forms an oligomeric tube on the host cell surface. Reminiscent of a double-stranded DNA phage tail in form and function, the H tube transports the single-stranded ÏX174 genome across the Escherichia coli cell wall. The 2.4-Å resolution H-tube crystal structure suggests functional and energetic mechanisms that may be common features of DNA transport through virally encoded conduits.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Proteínas Virais
/
DNA Viral
/
Bacteriófago phi X 174
/
Escherichia coli
Idioma:
En
Revista:
J Virol
Ano de publicação:
2014
Tipo de documento:
Article
País de afiliação:
Estados Unidos