A masquerading mass: an unusual presentation of IgG4-related systemic disease with tubulointerstitial nephritis.
J R Coll Physicians Edinb
; 44(2): 122-5, 2014.
Article
em En
| MEDLINE
| ID: mdl-24999772
ABSTRACT
IgG4 tubulointerstitial nephritis (IgG4-TIN) is the most common form of IgG4 renal disease. When IgG4-TIN is accompanied by other systemic manifestations the disease is known as IgG4-related systemic disease (IgG4-RSD). IgG4-RSD is well recognised in the form of tubulointerstitial nephritis (IgG4-related TIN) and may present with renal failure by mimicking neoplasms (tumefactive lesions) or with both features. We describe a case of IgG4-RSD initially presenting as a submandibular mass and subsequently presenting two years later with secondary infiltration of the kidney causing tubulointerstitial nephritis. This case highlights the importance of recognising IgG4-RSD as a non-malignant disease with presentations having commonly shared features including tumour-like swelling of involved organs and its ability to mimic many systemic diseases. In the majority of patients it can be treated successfully with corticosteroids.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sialadenite
/
Imunoglobulina G
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Nefrite Intersticial
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Humans
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Male
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Middle aged
Idioma:
En
Revista:
J R Coll Physicians Edinb
Assunto da revista:
EDUCACAO
/
HISTORIA DA MEDICINA
/
MEDICINA
Ano de publicação:
2014
Tipo de documento:
Article