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ABHD6 blockade exerts antiepileptic activity in PTZ-induced seizures and in spontaneous seizures in R6/2 mice.
Naydenov, Alipi V; Horne, Eric A; Cheah, Christine S; Swinney, Katie; Hsu, Ku-Lung; Cao, Jessica K; Marrs, William; Blankman, Jacqueline L; Tu, Sarah; Cherry, Allison E; Fung, Susan; Wen, Andy; Li, Weiwei; Saporito, Michael S; Selley, Dana E; Cravatt, Benjamin F; Oakley, John C; Stella, Nephi.
Afiliação
  • Naydenov AV; Medical Scientist Training Program, University of Washington, Seattle Washington, 98195, USA.
  • Horne EA; Neurobiology and Behavior Graduate Program, University of Washington, Seattle, Washington, 98195, USA.
  • Cheah CS; Department of Pharmacology, University of Washington, Seattle, Washington, 98195, USA.
  • Swinney K; Department of Pharmacology, University of Washington, Seattle, Washington, 98195, USA.
  • Hsu KL; Department of Pharmacology, University of Washington, Seattle, Washington, 98195, USA.
  • Cao JK; The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • Marrs W; Department of Pharmacology, University of Washington, Seattle, Washington, 98195, USA.
  • Blankman JL; Neurobiology and Behavior Graduate Program, University of Washington, Seattle, Washington, 98195, USA.
  • Tu S; The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • Cherry AE; Department of Pharmacology, University of Washington, Seattle, Washington, 98195, USA.
  • Fung S; Department of Pharmacology, University of Washington, Seattle, Washington, 98195, USA.
  • Wen A; Neurobiology and Behavior Graduate Program, University of Washington, Seattle, Washington, 98195, USA.
  • Li W; Department of Biology, University of Washington, Seattle, Washington, 98195, USA.
  • Saporito MS; The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • Selley DE; Melior Discovery, Inc., Exton, Pennsylvania, 19341, USA.
  • Cravatt BF; Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia, 23298, USA.
  • Oakley JC; The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, 92037, USA.
  • Stella N; Department of Pharmacology, University of Washington, Seattle, Washington, 98195, USA.
Neuron ; 83(2): 361-371, 2014 Jul 16.
Article em En | MEDLINE | ID: mdl-25033180
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Encéfalo / Carbamatos / Monoacilglicerol Lipases / Anticonvulsivantes Limite: Animals Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Convulsões / Encéfalo / Carbamatos / Monoacilglicerol Lipases / Anticonvulsivantes Limite: Animals Idioma: En Revista: Neuron Assunto da revista: NEUROLOGIA Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos