[5,6-bis-(3-alkoxy-carbonyl thio-ureido) benzimidazoles with anthelmintic activity]. / 5,6-bis(3-alkoxykarbonylthioureido) benzimidazoly s anthelmintickou úcinností.
Cesk Farm
; 38(3): 118-20, 1989 Apr.
Article
em Cs
| MEDLINE
| ID: mdl-2505937
ABSTRACT
The reaction of potassium thiocyanate with the methyl- and ethyl esters of chloroformic acid (V-VI) in acetone resulted in methoxy- and ethoxycarbonylisothiocyanates which were converted without isolation by means of an addition reaction with 2-alkyl-5,6-diaminobenzimidazoles (I-IV) into the pertinent 2-alkyl-5,6-bis (3-alkoxycarbonyl-2-thioureido) benzimidazoles (VII-XV). The substances obtained were tested for anthelmintic and anticoccidial effectiveness. In anthelmintic screening, substances VIII, IX, XI, XII, XIV and XV were significantly effective against the taenia Hymenolepis nana.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Anti-Helmínticos
Limite:
Animals
Idioma:
Cs
Revista:
Cesk Farm
Ano de publicação:
1989
Tipo de documento:
Article