Cognitive impairment in obstructive sleep apnea.
Pathol Biol (Paris)
; 62(5): 233-40, 2014 Oct.
Article
em En
| MEDLINE
| ID: mdl-25070768
ABSTRACT
Obstructive sleep apnea (OSA) is characterised by repetitive cessation or reduction of airflow due to upper airway obstructions. These respiratory events lead to chronic sleep fragmentation and intermittent hypoxemia. Several studies have shown that OSA is associated with daytime sleepiness and cognitive dysfunctions, characterized by impairments of attention, episodic memory, working memory, and executive functions. This paper reviews the cognitive profile of adults with OSA and discusses the relative role of altered sleep and hypoxemia in the aetiology of these cognitive deficits. Markers of cognitive dysfunctions such as those measured with waking electroencephalography and neuroimaging are also presented. The effects of continuous positive airway pressure (CPAP) on cognitive functioning and the possibility of permanent brain damage associated with OSA are also discussed. Finally, this paper reviews the evidence suggesting that OSA is a risk factor for developing mild cognitive impairment and dementia in the aging population and stresses the importance of its early diagnosis and treatment.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtornos Cognitivos
/
Apneia Obstrutiva do Sono
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Risk_factors_studies
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Screening_studies
Idioma:
En
Revista:
Pathol Biol (Paris)
Ano de publicação:
2014
Tipo de documento:
Article