[The atomic emission analysis under examination of composition of gallstones].

ABSTRACT

The high morbidity of cholelithiasis and considerable percentage of complications dictates necessity to search new little invasive modes of treatment. In this, one of the perspective directions is the application of dissolution of concrements using contact litholysis. The solubility of concrements directly depends on their composition. The detailed knowledge of composition of gallstones subjected to dissolution is needed for prognosis of solubility of concrements and experimental findings of new solvents. The mode of atomic emission analysis was applied to study mineral composition of 105 gallstones extracted from gallbladders of patients with cholelithiasis operated using laparoscopy. The experimental studies were implemented in vitro on dissolution of concrements depending on their composition and using octane acid. It is established that solubility of gallstones depends on content of calcium and ash composition of concrements. In consideration of relative simplicity of application, absence of complicated preparation of tests for analysis, distinct dependence of solubility of concrements on content of calcium and ash content of gallstones the atomic emission analysis can be recommended for examination of composition of gall concrements in case of search and development of new modes of litholysis. This mode of analysis can be also applied for prognosis of dissolution of concrements under application of contact litholysis.