A genome-wide survey of sexually dimorphic expression of Drosophila miRNAs identifies the steroid hormone-induced miRNA let-7 as a regulator of sexual identity.

Fagegaltier, Delphine; König, Annekatrin; Gordon, Assaf; Lai, Eric C; Gingeras, Thomas R; Hannon, Gregory J; Shcherbata, Halyna R

Fagegaltier, Delphine; König, Annekatrin; Gordon, Assaf; Lai, Eric C; Gingeras, Thomas R; Hannon, Gregory J; Shcherbata, Halyna R.

Afiliação

Fagegaltier D; Howard Hughes Medical Institute, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724 Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724 fagegalt@cshl.edu halyna.shcherbata@mpibpc.mpg.de.
König A; Max Planck Research Group of Gene Expression and Signaling, Max Planck Institute for Biophysical Chemistry, Göttingen 37077, Germany.
Gordon A; Howard Hughes Medical Institute, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724.
Lai EC; Department of Developmental Biology, Sloan-Kettering Institute, New York, New York 10065.
Gingeras TR; Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724.
Hannon GJ; Howard Hughes Medical Institute, Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724 Watson School of Biological Sciences, Cold Spring Harbor Laboratory, Cold Spring Harbor, New York 11724.
Shcherbata HR; Max Planck Research Group of Gene Expression and Signaling, Max Planck Institute for Biophysical Chemistry, Göttingen 37077, Germany fagegalt@cshl.edu halyna.shcherbata@mpibpc.mpg.de.

Genetics ; 198(2): 647-68, 2014 Oct.

Article em En | MEDLINE | ID: mdl-25081570

Assuntos

Drosophila melanogaster/genética; Ecdisteroides/fisiologia; MicroRNAs/genética; Animais; Linhagem Celular; Drosophila melanogaster/metabolismo; Feminino; Genoma de Inseto; Tecido Linfoide/citologia; Masculino; MicroRNAs/metabolismo; Especificidade de Órgãos; Ovário/metabolismo; Interferência de RNA; Caracteres Sexuais; Processos de Determinação Sexual; Testículo/metabolismo; Ativação Transcricional; Transcriptoma

Palavras-chave

Drosophila; development; ecdysteroid; genetics of sex; gonad; miRNA; sex determination

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ecdisteroides / MicroRNAs / Drosophila melanogaster Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Genetics Ano de publicação: 2014 Tipo de documento: Article

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