Enucleation after intraocular scrapie injection delays the spread of infection.
Brain Res
; 504(2): 301-5, 1989 Dec 18.
Article
em En
| MEDLINE
| ID: mdl-2513087
ABSTRACT
After right intraocular infection, mice develop lesions in the contralateral retinal projections long before clinical disease occurs. Enucleation up to 7 days post-infection prevented targeting of lesions to visual projections, and prolonged the incubation period. When enucleation was delayed until at least 14 days post-infection, lesion targeting and incubation periods were similar to unenucleated mice. It was concluded that infectivity took a minimum of 14 days to reach the brain via the optic nerve.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Scrapie
/
Príons
/
Colículos Superiores
/
Olho
Limite:
Animals
Idioma:
En
Revista:
Brain Res
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Reino Unido
País de publicação:
HOLANDA
/
HOLLAND
/
NETHERLANDS
/
NL
/
PAISES BAJOS
/
THE NETHERLANDS