Adipocyte plasma-membrane Gi and Gs in insulinopenic diabetic patients.
Biochem J
; 264(1): 289-92, 1989 Nov 15.
Article
em En
| MEDLINE
| ID: mdl-2513807
ABSTRACT
Changes in the amounts and functions of G-proteins have been reported in diabetic rats. We determined the Gi/Gs ratio of adipocyte plasma membranes in six insulinopenic diabetic patients and matched controls by immunoblotting with antisera against synthetic peptides corresponding to regions of G-proteins. No consistent changes in the Gi/Gs ratio were observed. It is still possible that the functional status of the G-proteins may be altered in diabetes.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Tecido Adiposo
/
Proteínas de Ligação ao GTP
/
Diabetes Mellitus
/
Insulina
Limite:
Humans
Idioma:
En
Revista:
Biochem J
Ano de publicação:
1989
Tipo de documento:
Article
País de afiliação:
Finlândia