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SAR405838: an optimized inhibitor of MDM2-p53 interaction that induces complete and durable tumor regression.
Wang, Shaomeng; Sun, Wei; Zhao, Yujun; McEachern, Donna; Meaux, Isabelle; Barrière, Cédric; Stuckey, Jeanne A; Meagher, Jennifer L; Bai, Longchuan; Liu, Liu; Hoffman-Luca, Cassandra Gianna; Lu, Jianfeng; Shangary, Sanjeev; Yu, Shanghai; Bernard, Denzil; Aguilar, Angelo; Dos-Santos, Odette; Besret, Laurent; Guerif, Stéphane; Pannier, Pascal; Gorge-Bernat, Dimitri; Debussche, Laurent.
Afiliação
  • Wang S; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan. Department of Pharmacology, University of Michigan, Ann Arbor, Michigan. Department of Medicinal Chemistry, University of Mic
  • Sun W; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Zhao Y; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • McEachern D; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Meaux I; Sanofi Oncology, Vitry-sur-Seine, France.
  • Barrière C; Sanofi Oncology, Vitry-sur-Seine, France.
  • Stuckey JA; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan.
  • Meagher JL; Life Sciences Institute, University of Michigan, Ann Arbor, Michigan.
  • Bai L; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Liu L; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Hoffman-Luca CG; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Pharmacology, University of Michigan, Ann Arbor, Michigan.
  • Lu J; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Shangary S; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Yu S; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Bernard D; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Aguilar A; University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.
  • Dos-Santos O; Sanofi Oncology, Vitry-sur-Seine, France.
  • Besret L; Sanofi Oncology, Vitry-sur-Seine, France.
  • Guerif S; Sanofi Oncology, Vitry-sur-Seine, France.
  • Pannier P; Sanofi Oncology, Vitry-sur-Seine, France.
  • Gorge-Bernat D; Sanofi Oncology, Vitry-sur-Seine, France.
  • Debussche L; Sanofi Oncology, Vitry-sur-Seine, France.
Cancer Res ; 74(20): 5855-65, 2014 Oct 15.
Article em En | MEDLINE | ID: mdl-25145672
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Espiro / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas c-mdm2 / Indóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2014 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos de Espiro / Proteína Supressora de Tumor p53 / Proteínas Proto-Oncogênicas c-mdm2 / Indóis / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Cancer Res Ano de publicação: 2014 Tipo de documento: Article