Bone marrow stromal stem cells transplantation in mice with acute spinal cord injury.
Methods Mol Biol
; 1213: 257-64, 2014.
Article
em En
| MEDLINE
| ID: mdl-25173389
ABSTRACT
Spinal cord injured experimental animals are widely used for studying pathophysiological processes after central nervous system acute traumatic lesion and elaborating therapeutic solutions, some of them based on stem cell transplantation. Here, we describe a protocol of spinal cord contusion in C57BL/6J mice, directly followed by bone marrow stromal stem cells transplantation. This model allows for the characterization of neuroprotective and neurorestorative abilities of these stem cells in a context of spinal cord trauma.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Traumatismos da Medula Espinal
/
Transplante de Medula Óssea
/
Células-Tronco Mesenquimais
Tipo de estudo:
Guideline
Limite:
Animals
Idioma:
En
Revista:
Methods Mol Biol
Assunto da revista:
BIOLOGIA MOLECULAR
Ano de publicação:
2014
Tipo de documento:
Article