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Proof-of-concept study demonstrating the pathogenicity of affinity-purified IgG antibodies directed to domain I of ß2-glycoprotein I in a mouse model of anti-phospholipid antibody-induced thrombosis.
Pericleous, Charis; Ruiz-Limón, Patricia; Romay-Penabad, Zurina; Marín, Ana Carrera; Garza-Garcia, Acely; Murfitt, Lucy; Driscoll, Paul C; Latchman, David S; Isenberg, David A; Giles, Ian; Ioannou, Yiannis; Rahman, Anisur; Pierangeli, Silvia S.
Afiliação
  • Pericleous C; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Ruiz-Limón P; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Romay-Penabad Z; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Marín AC; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Garza-Garcia A; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Murfitt L; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Driscoll PC; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Latchman DS; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Isenberg DA; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Giles I; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Ioannou Y; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Rahman A; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
  • Pierangeli SS; Centre for Rheumatology Research, Division of Medicine, University College London, London, UK, Division of Rheumatology, Department of Internal Medicine, University of Texas Medical Branch, Galveston, TX, USA, Structural Biology, Medical Research Council National Institute for Medical Research and A
Rheumatology (Oxford) ; 54(4): 722-7, 2015 Apr.
Article em En | MEDLINE | ID: mdl-25273993
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombose / Imunoglobulina G / Síndrome Antifosfolipídica / Anticorpos Antifosfolipídeos / Modelos Animais de Doenças / Beta 2-Glicoproteína I / Camundongos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Trombose / Imunoglobulina G / Síndrome Antifosfolipídica / Anticorpos Antifosfolipídeos / Modelos Animais de Doenças / Beta 2-Glicoproteína I / Camundongos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: Rheumatology (Oxford) Assunto da revista: REUMATOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de publicação: Reino Unido