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Response to Comment on "Oxytocin-mediated GABA inhibition during delivery attenuates autism pathogenesis in rodent offspring".
Eftekhari, Sanaz; Shahrokhi, Amene; Tsintsadze, Vera; Nardou, Romain; Brouchoud, Corinne; Conesa, Magali; Burnashev, Nail; Ferrari, Diana C; Ben-Ari, Yehezkel.
Afiliação
  • Eftekhari S; Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France. UMR 901, Aix-Marseille University, Marseille, France. Neurochlore, Campus Scientifique de Luminy, 163 Route de Luminy, Marseille, France. On leave from Iran University of Medical Sciences, Tehran, Iran.
  • Shahrokhi A; Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France. UMR 901, Aix-Marseille University, Marseille, France. Neurochlore, Campus Scientifique de Luminy, 163 Route de Luminy, Marseille, France. On leave from Tehran University of Medical Sciences, Tehran, Iran.
  • Tsintsadze V; Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France. UMR 901, Aix-Marseille University, Marseille, France.
  • Nardou R; Neurochlore, Campus Scientifique de Luminy, 163 Route de Luminy, Marseille, France.
  • Brouchoud C; Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France. UMR 901, Aix-Marseille University, Marseille, France.
  • Conesa M; Neurochlore, Campus Scientifique de Luminy, 163 Route de Luminy, Marseille, France.
  • Burnashev N; Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France. UMR 901, Aix-Marseille University, Marseille, France.
  • Ferrari DC; Neurochlore, Campus Scientifique de Luminy, 163 Route de Luminy, Marseille, France.
  • Ben-Ari Y; Mediterranean Institute of Neurobiology (INMED), U901, INSERM, Marseille, France. UMR 901, Aix-Marseille University, Marseille, France. Neurochlore, Campus Scientifique de Luminy, 163 Route de Luminy, Marseille, France. yehezkel.ben-ari@inserm.fr.
Science ; 346(6206): 176, 2014 Oct 10.
Article em En | MEDLINE | ID: mdl-25301611
ABSTRACT
Bambini-Junior et al. questioned whether our treatment in two rodent models of autism has a long-lasting effect into adulthood. In response, we show that bumetanide treatment around delivery attenuates autistic behavioral features in adult offspring. Therefore, the polarity of γ-aminobutyric acid (GABA) actions during delivery exerts long-lasting priming actions after birth.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Ocitocina / Citoproteção / Ácido gama-Aminobutírico Tipo de estudo: Etiology_studies Limite: Animals / Pregnancy Idioma: En Revista: Science Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Irã
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transtorno Autístico / Ocitocina / Citoproteção / Ácido gama-Aminobutírico Tipo de estudo: Etiology_studies Limite: Animals / Pregnancy Idioma: En Revista: Science Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Irã