Evaluation of intraabdominal adhesion generating potentials of ankaferd and calcium alginate used as hemostatic agents.
Bratisl Lek Listy
; 115(9): 544-9, 2014.
Article
em En
| MEDLINE
| ID: mdl-25318912
ABSTRACT
AIM:
The present study aimed to evaluate intra-abdominal adhesion generating potential of Ankaferd Blood Stopper (ABS), which was used as postoperative hemostatic agent in the rats that underwent surgery, in comparison with Ca-alginate. MATERIAL ANDMETHOD:
Totally, 30 rats were randomized into 4 groups. In the control group, 1x1 cm peritoneum was removed from the right lower quadrant after cecal abrasion. In the other two study groups, the same procedure was performed after Ankaferd Blood Stopper and Ca-alginate application respectively. RESULTS were evaluated both histopathologically and by adhesion scoring methods. All results underwent statistical analysis.RESULTS:
Comparing overall results, no statistically significant difference was found between the sham, control, ABS and Ca-alginate groups (p = 0.099). Paired group comparisons revealed no statistically significant difference between the sham group and the control, ABS, and Ca-alginate groups (p = 0.222, p = 0.222, and p = 0.833 respectively). It was observed that there was no statistically significant difference between the control and ABS groups (p = 0.505), but there was a statistically significant difference between the control and Ca-alginate groups with Bonferroni correction (p = 0.028). Histopathological examination revealed no statistical difference between the groups.CONCLUSION:
In conclusion, intra-abdominal adhesion generating potentials of Ca-alginate and ABS were experimentally evaluated and macroscopic and microscopic comparisons revealed no significant difference between sham, control, Ca-alginate, and ABS groups (Fig. 8, Ref. 36). Text in PDF www.elis.sk. agent.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hemostáticos
/
Extratos Vegetais
/
Doenças do Ceco
/
Hemorragia Pós-Operatória
/
Cavidade Abdominal
/
Alginatos
Tipo de estudo:
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
Bratisl Lek Listy
Ano de publicação:
2014
Tipo de documento:
Article