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TCRs genetically linked to CD28 and CD3ε do not mispair with endogenous TCR chains and mediate enhanced T cell persistence and anti-melanoma activity.
Govers, Coen; Sebestyén, Zsolt; Roszik, János; van Brakel, Mandy; Berrevoets, Cor; Szöor, Árpád; Panoutsopoulou, Konstantina; Broertjes, Marieke; Van, Tan; Vereb, György; Szöllosi, János; Debets, Reno.
Afiliação
  • Govers C; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus University Medical Center Cancer Institute, 3015 CN Rotterdam, the Netherlands;
  • Sebestyén Z; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus University Medical Center Cancer Institute, 3015 CN Rotterdam, the Netherlands;
  • Roszik J; Department of Biophysics and Cell Biology, University of Debrecen, 4032 Debrecen, Hungary; and.
  • van Brakel M; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus University Medical Center Cancer Institute, 3015 CN Rotterdam, the Netherlands;
  • Berrevoets C; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus University Medical Center Cancer Institute, 3015 CN Rotterdam, the Netherlands;
  • Szöor Á; Department of Biophysics and Cell Biology, University of Debrecen, 4032 Debrecen, Hungary; and.
  • Panoutsopoulou K; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus University Medical Center Cancer Institute, 3015 CN Rotterdam, the Netherlands;
  • Broertjes M; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus University Medical Center Cancer Institute, 3015 CN Rotterdam, the Netherlands;
  • Van T; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus University Medical Center Cancer Institute, 3015 CN Rotterdam, the Netherlands;
  • Vereb G; Department of Biophysics and Cell Biology, University of Debrecen, 4032 Debrecen, Hungary; and Cell Biology and Signaling Research Group of the Hungarian Academy of Sciences, Medical and Health Science Center, University of Debrecen, 4032 Debrecen, Hungary.
  • Szöllosi J; Department of Biophysics and Cell Biology, University of Debrecen, 4032 Debrecen, Hungary; and Cell Biology and Signaling Research Group of the Hungarian Academy of Sciences, Medical and Health Science Center, University of Debrecen, 4032 Debrecen, Hungary.
  • Debets R; Laboratory of Tumor Immunology, Department of Medical Oncology, Erasmus University Medical Center Cancer Institute, 3015 CN Rotterdam, the Netherlands; j.debets@erasmusmc.nl.
J Immunol ; 193(10): 5315-26, 2014 Nov 15.
Article em En | MEDLINE | ID: mdl-25320284

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Receptores de Antígenos de Linfócitos T / Linfócitos T / Complexo CD3 / Antígenos CD28 / Melanoma Tipo de estudo: Prognostic_studies Idioma: En Revista: J Immunol Ano de publicação: 2014 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Receptores de Antígenos de Linfócitos T / Linfócitos T / Complexo CD3 / Antígenos CD28 / Melanoma Tipo de estudo: Prognostic_studies Idioma: En Revista: J Immunol Ano de publicação: 2014 Tipo de documento: Article País de publicação: Estados Unidos