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Inhibition of endoplasmic reticulum-resident glucosidases impairs severe acute respiratory syndrome coronavirus and human coronavirus NL63 spike protein-mediated entry by altering the glycan processing of angiotensin I-converting enzyme 2.
Zhao, Xuesen; Guo, Fang; Comunale, Mary Ann; Mehta, Anand; Sehgal, Mohit; Jain, Pooja; Cuconati, Andrea; Lin, Hanxin; Block, Timothy M; Chang, Jinhong; Guo, Ju-Tao.
Afiliação
  • Zhao X; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA Baruch S. Blumberg Institute, Hepatitis B Foundation, Doylestown, Pennsylvania, USA.
  • Guo F; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA.
  • Comunale MA; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA.
  • Mehta A; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA.
  • Sehgal M; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA.
  • Jain P; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA.
  • Cuconati A; Baruch S. Blumberg Institute, Hepatitis B Foundation, Doylestown, Pennsylvania, USA.
  • Lin H; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada.
  • Block TM; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA Baruch S. Blumberg Institute, Hepatitis B Foundation, Doylestown, Pennsylvania, USA.
  • Chang J; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA.
  • Guo JT; Drexel Institute for Biotechnology and Virology Research, Department of Microbiology and Immunology, Drexel University College of Medicine, Doylestown, Pennsylvania, USA Ju-Tao.Guo@drexelmed.edu.
Antimicrob Agents Chemother ; 59(1): 206-16, 2015 Jan.
Article em En | MEDLINE | ID: mdl-25348530
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Peptidil Dipeptidase A / Coronavírus Relacionado à Síndrome Respiratória Aguda Grave / Internalização do Vírus / Coronavirus Humano NL63 / Glucosidases Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Peptidil Dipeptidase A / Coronavírus Relacionado à Síndrome Respiratória Aguda Grave / Internalização do Vírus / Coronavirus Humano NL63 / Glucosidases Limite: Humans Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos