Sample processing obscures cancer-specific alterations in leukemic transcriptomes.

Dvinge, Heidi; Ries, Rhonda E; Ilagan, Janine O; Stirewalt, Derek L; Meshinchi, Soheil; Bradley, Robert K

Dvinge, Heidi; Ries, Rhonda E; Ilagan, Janine O; Stirewalt, Derek L; Meshinchi, Soheil; Bradley, Robert K.

Afiliação

Dvinge H; Computational Biology Program, Public Health Sciences Division, Basic Sciences Division, and.
Ries RE; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109; and.
Ilagan JO; Computational Biology Program, Public Health Sciences Division, Basic Sciences Division, and.
Stirewalt DL; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109; and.
Meshinchi S; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109; and Division of Pediatric Hematology/Oncology, School of Medicine, University of Washington, Seattle, WA 98195.
Bradley RK; Computational Biology Program, Public Health Sciences Division, Basic Sciences Division, and rbradley@fhcrc.org.

Proc Natl Acad Sci U S A ; 111(47): 16802-7, 2014 Nov 25.

Article em En | MEDLINE | ID: mdl-25385641

Assuntos

Leucemia/genética; Transcriptoma; Genoma Humano; Humanos; Leucemia/imunologia; Ativação Linfocitária; NF-kappa B/metabolismo; Splicing de RNA; Transdução de Sinais

Palavras-chave

RNA splicing; batch effects; leukemia; nonsense-mediated decay

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia / Transcriptoma Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2014 Tipo de documento: Article País de publicação: Estados Unidos

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