LC-MS/MS simultaneous quantitation of 2-hydroxyethylated, oxidative, and unmodified DNA nucleosides in DNA isolated from tissues of mice after exposure to ethylene oxide.

Zhang, Fagen; Bartels, Michael J; LeBaron, Matthew J; Schisler, Melissa R; Jeong, Yo-Chan; Gollapudi, B Bhaskar; Moore, Nigel P

Zhang, Fagen; Bartels, Michael J; LeBaron, Matthew J; Schisler, Melissa R; Jeong, Yo-Chan; Gollapudi, B Bhaskar; Moore, Nigel P.

Afiliação

Zhang F; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, 1803 Building, Midland, MI 48674, USA. Electronic address: fzzhang@dow.com.
Bartels MJ; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, 1803 Building, Midland, MI 48674, USA.
LeBaron MJ; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, 1803 Building, Midland, MI 48674, USA.
Schisler MR; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, 1803 Building, Midland, MI 48674, USA.
Jeong YC; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, 1803 Building, Midland, MI 48674, USA.
Gollapudi BB; Toxicology and Environmental Research & Consulting, The Dow Chemical Company, 1803 Building, Midland, MI 48674, USA.
Moore NP; Toxicology and Environmental Research & Consulting, Dow Europe GmbH Horgen, Switzerland.

J Chromatogr B Analyt Technol Biomed Life Sci ; 976-977: 33-48, 2015 Jan 22.

Article em En | MEDLINE | ID: mdl-25529473

Assuntos

DNA/análise; DNA/química; Óxido de Etileno/farmacologia; Nucleosídeos/análise; Nucleosídeos/química; Animais; Cromatografia Líquida; Masculino; Camundongos; Espectrometria de Massas em Tandem

Palavras-chave

2-Hydroxyethylated and oxidative DNA nucleoside biomarkers; Ethylene oxide; Liquid chromatography tandem mass spectrometry; Simultaneous quantitation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Óxido de Etileno / Nucleosídeos Limite: Animals Idioma: En Revista: J Chromatogr B Analyt Technol Biomed Life Sci Assunto da revista: ENGENHARIA BIOMEDICA Ano de publicação: 2015 Tipo de documento: Article País de publicação: Holanda

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