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The cerebral cavernous malformation pathway controls cardiac development via regulation of endocardial MEKK3 signaling and KLF expression.
Zhou, Zinan; Rawnsley, David R; Goddard, Lauren M; Pan, Wei; Cao, Xing-Jun; Jakus, Zoltan; Zheng, Hui; Yang, Jisheng; Arthur, J Simon C; Whitehead, Kevin J; Li, Dean; Zhou, Bin; Garcia, Benjamin A; Zheng, Xiangjian; Kahn, Mark L.
Afiliação
  • Zhou Z; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Rawnsley DR; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Goddard LM; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Pan W; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Cao XJ; Department of Biochemistry and Biophysics, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Jakus Z; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Zheng H; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Yang J; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Arthur JS; Division of Cell Signaling and Immunology, University of Dundee, Dundee DD1 5EH, UK.
  • Whitehead KJ; Division of Cardiovascular Medicine and the Program in Molecular Medicine, University of Utah, Salt Lake City, UT 84112, USA.
  • Li D; Division of Cardiovascular Medicine and the Program in Molecular Medicine, University of Utah, Salt Lake City, UT 84112, USA; The Key Laboratory for Human Disease Gene Study of Sichuan Province, Institute of Laboratory Medicine, Sichuan Academy of Medical Sciences & Sichuan Provincial People's H
  • Zhou B; Department of Genetics, Pediatric, and Medicine (Cardiology) and Wilf Cardiovascular Research Institute, Albert Einstein College of Medicine of Yeshiva University, 1301 Morris Park Avenue, Bronx, NY 10461, USA.
  • Garcia BA; Department of Biochemistry and Biophysics, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
  • Zheng X; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA; Lab of Cardiovascular Signaling, Centenary Institute, Sydney NSW 2050, Australia. Electronic address: x.zheng@centenary.org.au.
  • Kahn ML; Department of Medicine and Cardiovascular Institute, University of Pennsylvania, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA. Electronic address: markkahn@mail.med.upenn.edu.
Dev Cell ; 32(2): 168-80, 2015 Jan 26.
Article em En | MEDLINE | ID: mdl-25625206
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases Ativadas por Mitógeno / Sistema de Sinalização das MAP Quinases / Células Endoteliais / MAP Quinase Quinase Quinase 3 / Endocárdio / Fatores de Transcrição Kruppel-Like / Proteínas Associadas aos Microtúbulos Limite: Animals Idioma: En Revista: Dev Cell Assunto da revista: EMBRIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Quinases Ativadas por Mitógeno / Sistema de Sinalização das MAP Quinases / Células Endoteliais / MAP Quinase Quinase Quinase 3 / Endocárdio / Fatores de Transcrição Kruppel-Like / Proteínas Associadas aos Microtúbulos Limite: Animals Idioma: En Revista: Dev Cell Assunto da revista: EMBRIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos