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AML cells have low spare reserve capacity in their respiratory chain that renders them susceptible to oxidative metabolic stress.
Sriskanthadevan, Shrivani; Jeyaraju, Danny V; Chung, Timothy E; Prabha, Swayam; Xu, Wei; Skrtic, Marko; Jhas, Bozhena; Hurren, Rose; Gronda, Marcela; Wang, Xiaoming; Jitkova, Yulia; Sukhai, Mahadeo A; Lin, Feng-Hsu; Maclean, Neil; Laister, Rob; Goard, Carolyn A; Mullen, Peter J; Xie, Stephanie; Penn, Linda Z; Rogers, Ian M; Dick, John E; Minden, Mark D; Schimmer, Aaron D.
Afiliação
  • Sriskanthadevan S; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Jeyaraju DV; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Chung TE; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Prabha S; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Xu W; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Skrtic M; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Jhas B; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Hurren R; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Gronda M; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Wang X; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Jitkova Y; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Sukhai MA; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Lin FH; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Maclean N; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Laister R; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Goard CA; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Mullen PJ; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Xie S; Division of Stem Cell and Developmental Biology, Campbell Family Institute for Cancer Research/Ontario Cancer Institute, Toronto, ON, Canada; and.
  • Penn LZ; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Rogers IM; Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.
  • Dick JE; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada; Division of Stem Cell and Developmental Biology, Campbell Family Institute for Cancer Research/Ontario Cancer Institute, Toronto, ON, Canada; and.
  • Minden MD; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
  • Schimmer AD; Princess Margaret Cancer Centre, Ontario Cancer Institute, Toronto, ON, Canada;
Blood ; 125(13): 2120-30, 2015 Mar 26.
Article em En | MEDLINE | ID: mdl-25631767
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Consumo de Oxigênio / Leucemia Mieloide Aguda / Estresse Oxidativo Limite: Humans Idioma: En Revista: Blood Ano de publicação: 2015 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Consumo de Oxigênio / Leucemia Mieloide Aguda / Estresse Oxidativo Limite: Humans Idioma: En Revista: Blood Ano de publicação: 2015 Tipo de documento: Article País de publicação: Estados Unidos