Oasis: online analysis of small RNA deep sequencing data.
Bioinformatics
; 31(13): 2205-7, 2015 Jul 01.
Article
em En
| MEDLINE
| ID: mdl-25701573
ABSTRACT
UNLABELLED Oasis is a web application that allows for the fast and flexible online analysis of small-RNA-seq (sRNA-seq) data. It was designed for the end user in the lab, providing an easy-to-use web frontend including video tutorials, demo data and best practice step-by-step guidelines on how to analyze sRNA-seq data. Oasis' exclusive selling points are a differential expression module that allows for the multivariate analysis of samples, a classification module for robust biomarker detection and an advanced programming interface that supports the batch submission of jobs. Both modules include the analysis of novel miRNAs, miRNA targets and functional analyses including GO and pathway enrichment. Oasis generates downloadable interactive web reports for easy visualization, exploration and analysis of data on a local system. Finally, Oasis' modular workflow enables for the rapid (re-) analysis of data. AVAILABILITY AND IMPLEMENTATION Oasis is implemented in Python, R, Java, PHP, C++ and JavaScript. It is freely available at http//oasis.dzne.de. CONTACT stefan.bonn@dzne.de SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Software
/
Sistemas On-Line
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Análise de Sequência de RNA
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Biologia Computacional
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MicroRNAs
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Sequenciamento de Nucleotídeos em Larga Escala
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
En
Revista:
Bioinformatics
Assunto da revista:
INFORMATICA MEDICA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Alemanha