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Peripheral circulation evaluation with near-infrared spectroscopy in skeletal muscle during cardiopulmonary bypass.
Mukaida, H; Matsushita, S; Inotani, T; Futaki, S; Takano, A; Watanabe, M; Morita, T; Miida, T; Amano, A.
Afiliação
  • Mukaida H; Department of Clinical Engineering, Juntendo University Hospital, Tokyo, Japan.
  • Matsushita S; Department of Cardiovascular Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan saty-m@juntendo.ac.jp.
  • Inotani T; Department of Clinical Engineering, Juntendo University Hospital, Tokyo, Japan.
  • Futaki S; Department of Clinical Engineering, Juntendo University Hospital, Tokyo, Japan.
  • Takano A; Department of Clinical Engineering, Juntendo University Hospital, Tokyo, Japan.
  • Watanabe M; Department of Clinical Engineering, Juntendo University Hospital, Tokyo, Japan.
  • Morita T; Department of Cardiovascular Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
  • Miida T; Department of Clinical Laboratory Medicine, Juntendo University, Faculty of Medicine, Tokyo, Japan.
  • Amano A; Department of Cardiovascular Surgery, Juntendo University, Faculty of Medicine, Tokyo, Japan.
Perfusion ; 30(8): 653-9, 2015 Nov.
Article em En | MEDLINE | ID: mdl-25721457
BACKGROUND: We designed a non-invasive, observational, real-time study, using near-infrared spectroscopy (NIRS) to assess the in vivo effects of cardiopulmonary bypass (CPB) on patients' skeletal muscle as well as the effects of hemodilution and hypothermia on tissue oxygen delivery during CPB. METHODS: The study included 20 consecutive adult patients undergoing open-heart surgery with CPB. Evaluation parameters for peripheral circulation were measured using the NIRO-200NX and recorded every 30 seconds. To assess how hemodilution influences peripheral circulation parameters, we compared data between a group of patients with hematocrit (Hct) values >22% (high Hct group) and those with Hct values ⩽22% (low Hct group). RESULTS: Changes in the concentration of oxygenated hemoglobin (ΔO2Hb, µmol/L), which flows into the skeletal muscle, was an important factor for deciding the tissue oxygenation index (TOI%), showing the tissue oxygen saturation. The low Hct group showed a significant increase in the normalized tissue hemoglobin index (nTHI), showing the percentage change in the amount of initial hemoglobin and TOI compared to the high Hct group. Changes in the concentration of oxygenated hemoglobin (ΔO2Hb, µmol/L) and deoxygenated hemoglobin (ΔHHb, µmol/L) were significantly less in the low Hct group than in the high Hct group, thus, showing good peripheral circulation despite the low hematocrit levels. CONCLUSION: Our study indicated the presence of a compensatory mechanism in which increased blood flow of the microcirculation is in compensation for the lack of oxyhemoglobin delivery caused by hemodilution.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ponte Cardiopulmonar / Músculo Esquelético / Hemodiluição / Microcirculação Tipo de estudo: Observational_studies Limite: Adult / Aged / Humans / Middle aged Idioma: En Revista: Perfusion Assunto da revista: CARDIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ponte Cardiopulmonar / Músculo Esquelético / Hemodiluição / Microcirculação Tipo de estudo: Observational_studies Limite: Adult / Aged / Humans / Middle aged Idioma: En Revista: Perfusion Assunto da revista: CARDIOLOGIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido