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Value of 18-F-FDG PET/CT and CT in the Diagnosis of Indeterminate Adrenal Masses.
Launay, Nathalie; Silvera, Stéphane; Tenenbaum, Florence; Groussin, Lionel; Tissier, Frédérique; Audureau, Etienne; Vignaux, Olivier; Dousset, Bertrand; Bertagna, Xavier; Legmann, Paul.
Afiliação
  • Launay N; Department of Radiology, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France ; Sorbonne Paris Cité, Université Paris Descartes, 12 rue de l'École de Medicine, 75006 Paris, France.
  • Silvera S; Department of Radiology, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France.
  • Tenenbaum F; Department of Nuclear Medicine, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France.
  • Groussin L; Sorbonne Paris Cité, Université Paris Descartes, 12 rue de l'École de Medicine, 75006 Paris, France ; Department of Endocrinology, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France.
  • Tissier F; Sorbonne Paris Cité, Université Paris Descartes, 12 rue de l'École de Medicine, 75006 Paris, France ; Department of Anatomopathology, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France.
  • Audureau E; Sorbonne Paris Cité, Université Paris Descartes, 12 rue de l'École de Medicine, 75006 Paris, France ; Department of Epidemiology and Biostatistics, Hôtel Dieu University Hospital, 1 Parvis Notre Dame-place Jean Paul II, 75004 Paris, France.
  • Vignaux O; Department of Radiology, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France ; Sorbonne Paris Cité, Université Paris Descartes, 12 rue de l'École de Medicine, 75006 Paris, France.
  • Dousset B; Sorbonne Paris Cité, Université Paris Descartes, 12 rue de l'École de Medicine, 75006 Paris, France ; Department of Digestive and Endocrine Surgery, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France.
  • Bertagna X; Sorbonne Paris Cité, Université Paris Descartes, 12 rue de l'École de Medicine, 75006 Paris, France ; Department of Endocrinology, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France.
  • Legmann P; Department of Radiology, Cochin University Hospital, 27 rue du Faubourg St. Jacques, 75014 Paris, France ; Sorbonne Paris Cité, Université Paris Descartes, 12 rue de l'École de Medicine, 75006 Paris, France.
Int J Endocrinol ; 2015: 213875, 2015.
Article em En | MEDLINE | ID: mdl-25722719
The purpose of this paper was to study the value of 18-FDG PET/CT and reassess the value of CT for the characterization of indeterminate adrenal masses. 66 patients with 67 indeterminate adrenal masses were included in our study. CT/MRI images and 18F-FDG PET/CT data were evaluated blindly for tumor morphology, enhancement features, apparent diffusion coefficient values, maximum standardized uptake values, and adrenal-to-liver maxSUV ratio. The study population comprised pathologically confirmed 16 adenomas, 19 metastases, and 32 adrenocortical carcinomas. Macroscopic fat was observed in 62.5% of the atypical adenomas at CT but not in malignant masses. On 18F-FDG PET/CT, SUVmax and adrenal-to-liver maxSUV ratio were significantly lower in adenomas than in malignant tumors. An SUVmax value of less than 3.7 or an adrenal-to-liver maxSUV ratio of less than 1.29 is highly predictive of benignity.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Int J Endocrinol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: França País de publicação: Egito

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Diagnostic_studies Idioma: En Revista: Int J Endocrinol Ano de publicação: 2015 Tipo de documento: Article País de afiliação: França País de publicação: Egito