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Real-time monitoring of binding events on a thermostabilized human A2A receptor embedded in a lipid bilayer by surface plasmon resonance.
Bocquet, Nicolas; Kohler, Josiane; Hug, Melanie N; Kusznir, Eric A; Rufer, Arne C; Dawson, Roger J; Hennig, Michael; Ruf, Armin; Huber, Walter; Huber, Sylwia.
Afiliação
  • Bocquet N; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Molecular Design and Chemical Biology, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland. Electronic address: nicolas.bocquet@roche.com.
  • Kohler J; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Molecular Design and Chemical Biology, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
  • Hug MN; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Molecular Design and Chemical Biology, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
  • Kusznir EA; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Molecular Design and Chemical Biology, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
  • Rufer AC; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Molecular Design and Chemical Biology, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
  • Dawson RJ; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Discovery Technologies, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
  • Hennig M; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Discovery Technologies, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
  • Ruf A; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Molecular Design and Chemical Biology, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
  • Huber W; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Molecular Design and Chemical Biology, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
  • Huber S; F. Hoffmann-La Roche, Pharma Research and Early Development (pRED), Molecular Design and Chemical Biology, Roche Innovation Center Basel, Grenzacherstrasse 124, Basel CH4070, Switzerland.
Biochim Biophys Acta ; 1848(5): 1224-33, 2015 May.
Article em En | MEDLINE | ID: mdl-25725488

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Temperatura / Ressonância de Plasmônio de Superfície / Receptor A2A de Adenosina / Antagonistas do Receptor A2 de Adenosina / Bicamadas Lipídicas / Lipídeos de Membrana Limite: Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2015 Tipo de documento: Article País de publicação: Holanda

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Temperatura / Ressonância de Plasmônio de Superfície / Receptor A2A de Adenosina / Antagonistas do Receptor A2 de Adenosina / Bicamadas Lipídicas / Lipídeos de Membrana Limite: Humans Idioma: En Revista: Biochim Biophys Acta Ano de publicação: 2015 Tipo de documento: Article País de publicação: Holanda