Making animals alcoholic: shifting laboratory models of addiction.
J Hist Behav Sci
; 51(2): 164-94, 2015.
Article
em En
| MEDLINE
| ID: mdl-25740698
ABSTRACT
The use of animals as experimental organisms has been critical to the development of addiction research from the nineteenth century. They have been used as a means of generating reliable data regarding the processes of addiction that was not available from the study of human subjects. Their use, however, has been far from straightforward. Through focusing on the study of alcoholism, where the nonhuman animal proved a most reluctant collaborator, this paper will analyze the ways in which scientists attempted to deal with its determined sobriety and account for their consistent failure to replicate the volitional consumption of ethanol to the point of physical dependency. In doing so, we will see how the animal model not only served as a means of interrogating a complex pathology, but also came to embody competing definitions of alcoholism as a disease process, and alternative visions for the very structure and purpose of a research field.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psicologia Experimental
/
Experimentação Animal
/
Modelos Animais de Doenças
/
Alcoolismo
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Revista:
J Hist Behav Sci
Ano de publicação:
2015
Tipo de documento:
Article