Toxoplasma gondii Exposure and the Risk of Schizophrenia.
Jundishapur J Microbiol
; 7(11): e12776, 2014 Nov.
Article
em En
| MEDLINE
| ID: mdl-25774275
ABSTRACT
BACKGROUND:
Schizophrenia is a major psychiatric disorder with a deeply destructive pathophysiology. There are evidences to indicate that infectious agents such as Toxoplasma gondii may play some roles in etiology of the disorder.OBJECTIVES:
The current study aimed to determine the association between T. gondii exposure and the risk of schizophrenia. MATERIALS ANDMETHODS:
T. gondii IgG antibodies of 100 patients with schizophrenia as well as 200 healthy volunteers were assessed. The subjects also completed demographic questionnaires. Data was analyzed using the chi-square and Fisher exact tests.RESULTS:
The analyses confirmed the significant differences between healthy women and ones with schizophrenia (P = 0.001) as well as between males and females with schizophrenia (P = 0.009) in IgG positivity.CONCLUSIONS:
The present study supported the contamination with T. gondii as a risk factor for schizophrenia just in women.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Jundishapur J Microbiol
Ano de publicação:
2014
Tipo de documento:
Article