[Metabotropic receptor of the group I of the 5th subtype (ImGLuR5) in honeybee associative olfactory learning].
Zh Evol Biokhim Fiziol
; 50(3): 219-25, 2014.
Article
em Ru
| MEDLINE
| ID: mdl-25775856
ABSTRACT
The work deals with study of character of localization in the honeybee head ganglion of metabotropic receptor ImGluR5 and its role in memory formation. With aid of pharmacological method (injections of antisense oligonucleotide and of selective receptor agonist and antagonist) and of behavioral criterion (formation and testing of preservation in memory of conditioned alimentary reflex for olfactory stimulus), there is first shown participation of the studied receptor in formation of the honeybee long-term memory. By using the immunohistochemical method, there is first revealed the predominant expression of the ImGluR5 receptor in the mushroom body Canyon cells responsible for the insect integrative activity. The present study, together with the previous ones, allows concluding about the presence in the honeybee head ganglion of the group I of metabotropic glutamate receptors with two subtypes 1 and 5 (ImGluR1,5) that have similar with mammalian pharmacological properties favoring preservation of the individually acquired experience in the long-term memory.
Buscar no Google
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Aprendizagem por Associação
/
Receptores de Ácido Caínico
/
Proteínas de Insetos
/
Memória de Longo Prazo
Tipo de estudo:
Risk_factors_studies
Limite:
Animals
Idioma:
Ru
Revista:
Zh Evol Biokhim Fiziol
Ano de publicação:
2014
Tipo de documento:
Article