HDL particle subpopulations: Focus on biological function.
Biofactors
; 41(2): 67-77, 2015.
Article
em En
| MEDLINE
| ID: mdl-25809447
ABSTRACT
Low levels of high-density lipoprotein-cholesterol (HDL-C) constitute an independent biomarker of cardiovascular morbi-mortality. However, recent advances have drastically modified the classical and limited view of HDL as a carrier of 'good cholesterol', and have revealed unexpected levels of complexity in the circulating HDL particle pool. HDL particles are indeed highly heterogeneous in structure, intravascular metabolism and biological activity. This review describes recent progress in our understanding of HDL subpopulations and their biological activities, and focuses on relationships between the structural, compositional and functional heterogeneity of HDL particles.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vasodilatadores
/
Doenças Cardiovasculares
/
Anti-Inflamatórios não Esteroides
/
Fibrinolíticos
/
HDL-Colesterol
/
Antioxidantes
Limite:
Animals
/
Humans
Idioma:
En
Revista:
Biofactors
Assunto da revista:
BIOQUIMICA
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Brasil