The utility of three-dimensional optical projection tomography in nerve injection injury imaging.
Anaesthesia
; 70(8): 939-47, 2015 Aug.
Article
em En
| MEDLINE
| ID: mdl-25827062
ABSTRACT
The examination of nerve microarchitecture has hitherto been limited solely to two-dimensional imaging techniques. The objective of this study was to evaluate the ability of optical projection tomography to discern the nerve microarchitecture and injection injury in three dimensions. Five piglets were studied, whose median and lingual nerves were unilaterally injected post mortem with preset volumes of local anaesthetic, excised and subsequently made transparent with benzyl alcohol benzyl benzoate. Images were captured in three dimensions. The same contralateral nerves were used as controls. Using optical projection tomography, we observed differences between the internal organisation of the median and the lingual nerves, which potentially explain the variations in their susceptibility to injury. This was demonstrated in three dimensions as a disruption to the fascicles in the lingual nerve, and their displacement in the median nerve. This new technology offers potential for studying nerve microarchitecture topography and its tolerance to injection injury.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Imageamento Tridimensional
/
Tomografia Óptica
/
Traumatismos do Nervo Lingual
/
Nervo Mediano
/
Bloqueio Nervoso
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Limite:
Animals
Idioma:
En
Revista:
Anaesthesia
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Eslovênia