Serum IgG and IgA levels in polio and non-polio acute flaccid paralysis cases in western Uttar Pradesh, India.
Indian Pediatr
; 52(3): 220-2, 2015 Mar 08.
Article
em En
| MEDLINE
| ID: mdl-25848998
ABSTRACT
OBJECTIVE:
IgG and IgA immunocompetence of children with wild poliovirus poliomyelitis and non-polio acute flaccid paralysis.METHODS:
932 cases of acute flaccid paralysis, reported in 2008-2009, were tested for presence of polio and non-polio enteroviruses according to the WHO standards. Serum IgA and IgG levels were determined by sandwich ELISA.RESULTS:
Mean (SD) IgA levels [0.87 (0.62)g/L; n=28] of virologically confirmed poliomyelitis cases were lower than those of virus negative [1.21 (0.83)g/L; n=612] and non-polio Enterovirus positive [1.22 (0.79)g/L; n=240] cases of acute flaccid paralysis. No significant difference was observed in the concentration of IgG among these groups.CONCLUSIONS:
IgA plays an important role in protection against poliomyelitis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Paraplegia
/
Poliomielite
/
Imunoglobulina A
/
Imunoglobulina G
Limite:
Child, preschool
/
Humans
/
Infant
/
Newborn
País/Região como assunto:
Asia
Idioma:
En
Revista:
Indian Pediatr
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Índia