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No association between iron status and self-reported health-related quality of life in 16,375 Danish blood donors: results from the Danish Blood Donor Study.
Rigas, Andreas S; Pedersen, Ole B; Sørensen, Cecilie J; Sørensen, Erik; Kotzé, Sebastian R; Petersen, Mikkel S; Thørner, Lise W; Hjalgrim, Henrik; Erikstrup, Christian; Ullum, Henrik.
Afiliação
  • Rigas AS; Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Pedersen OB; Department of Clinical Immunology, Naestved Hospital, Naestved, Denmark.
  • Sørensen CJ; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
  • Sørensen E; Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Kotzé SR; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
  • Petersen MS; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
  • Thørner LW; Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
  • Hjalgrim H; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark.
  • Erikstrup C; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.
  • Ullum H; Department of Clinical Immunology, Copenhagen University Hospital, Copenhagen, Denmark.
Transfusion ; 55(7): 1752-6, 2015 Jul.
Article em En | MEDLINE | ID: mdl-25851623
ABSTRACT

BACKGROUND:

Health-related quality of life (HRQL) represents people's subjective assessment of their mental and physical well-being. HRQL is highly predictive of future health. The effect of iron deficiency without anemia induced by blood donation on HRQL is presently unknown. The aim was to explore the relationship between iron status and self-reported mental component score (MCS; SF-12) and physical component score (PCS; SF-12) in Danish blood donors. STUDY DESIGN AND

METHODS:

Complete relevant data, including the 12-item short-form health survey (SF-12), plasma ferritin levels, age, body mass index, smoking status, C-reactive protein levels, number of donations in the previous 3 years, and PCS and MCS, were available for 8692 men and 7683 women enrolled from March 1, 2010, to December 31, 2010. Multivariable linear and logistic (cutoff at the 10th percentile) regression analyses were used to assess the relationship between iron deficiency (ferritin < 15 ng/mL) and MCS and PCS, respectively. Analyses were performed separately for men and women.

RESULTS:

There was no significant relationship between iron deficiency and self-reported mental or physical health.

CONCLUSION:

This study found no association between iron stores and self-reported HRQL among Danish blood donors.
Assuntos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Doadores de Sangue / Saúde Mental / Ferritinas / Autorrelato / Ferro Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Transfusion Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Dinamarca

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Qualidade de Vida / Doadores de Sangue / Saúde Mental / Ferritinas / Autorrelato / Ferro Tipo de estudo: Clinical_trials / Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Aspecto: Patient_preference Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged País/Região como assunto: Europa Idioma: En Revista: Transfusion Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Dinamarca