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Neuronal development is promoted by weakened intrinsic antioxidant defences due to epigenetic repression of Nrf2.
Bell, Karen F S; Al-Mubarak, Bashayer; Martel, Marc-André; McKay, Sean; Wheelan, Nicola; Hasel, Philip; Márkus, Nóra M; Baxter, Paul; Deighton, Ruth F; Serio, Andrea; Bilican, Bilada; Chowdhry, Sudhir; Meakin, Paul J; Ashford, Michael L J; Wyllie, David J A; Scannevin, Robert H; Chandran, Siddharthan; Hayes, John D; Hardingham, Giles E.
Afiliação
  • Bell KF; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Al-Mubarak B; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Martel MA; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • McKay S; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Wheelan N; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Hasel P; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Márkus NM; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Baxter P; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Deighton RF; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Serio A; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4SB, UK.
  • Bilican B; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4SB, UK.
  • Chowdhry S; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
  • Meakin PJ; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
  • Ashford ML; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
  • Wyllie DJ; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Scannevin RH; Biogen Idec, 14 Cambridge Center, Cambridge, Massachusetts 02142, USA.
  • Chandran S; MRC Centre for Regenerative Medicine, University of Edinburgh, Edinburgh EH16 4SB, UK.
  • Hayes JD; Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK.
  • Hardingham GE; Centre for Integrative Physiology, University of Edinburgh, Edinburgh EH8 9XD, UK.
Nat Commun ; 6: 7066, 2015 May 13.
Article em En | MEDLINE | ID: mdl-25967870
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Regulação da Expressão Gênica no Desenvolvimento / Epigênese Genética / Fator 2 Relacionado a NF-E2 / Neurônios / Antioxidantes Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Regulação da Expressão Gênica no Desenvolvimento / Epigênese Genética / Fator 2 Relacionado a NF-E2 / Neurônios / Antioxidantes Limite: Animals Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Reino Unido