Stereospecific suppression of active site mutants by methylphosphonate substituted substrates reveals the stereochemical course of site-specific DNA recombination.

Rowley, Paul A; Kachroo, Aashiq H; Ma, Chien-Hui; Maciaszek, Anna D; Guga, Piotr; Jayaram, Makkuni

Rowley, Paul A; Kachroo, Aashiq H; Ma, Chien-Hui; Maciaszek, Anna D; Guga, Piotr; Jayaram, Makkuni.

Afiliação

Rowley PA; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
Kachroo AH; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
Ma CH; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA.
Maciaszek AD; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Department of Bioorganic Chemistry, Sienkiewicza 112, 90-363 Lodz, Poland.
Guga P; Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Department of Bioorganic Chemistry, Sienkiewicza 112, 90-363 Lodz, Poland.
Jayaram M; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA jayaram@austin.utexas.edu.

Nucleic Acids Res ; 43(12): 6023-37, 2015 Jul 13.

Article em En | MEDLINE | ID: mdl-25999343

Assuntos

Arginina/química; DNA Nucleotidiltransferases/química; Integrases/química; Compostos Organofosforados/química; Recombinação Genética; DNA/química; DNA/metabolismo; DNA Nucleotidiltransferases/genética; DNA Nucleotidiltransferases/metabolismo; Integrases/genética; Integrases/metabolismo; Mutação; Estereoisomerismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Organofosforados / Arginina / Recombinação Genética / Integrases / DNA Nucleotidiltransferases Idioma: En Revista: Nucleic Acids Res Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Estados Unidos

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