Activation of RAW 264.7 cells by a polysaccharide isolated from Antarctic bacterium Pseudoaltermonas sp. S-5.

Li, Jing; Qian, Wen; Xu, Yanghui; Chen, Guochuang; Wang, Guodong; Nie, Songliu; Shen, Bingxiang; Zhao, Zhigang; Liu, Chunyan; Chen, Kaoshan

Li, Jing; Qian, Wen; Xu, Yanghui; Chen, Guochuang; Wang, Guodong; Nie, Songliu; Shen, Bingxiang; Zhao, Zhigang; Liu, Chunyan; Chen, Kaoshan.

Afiliação

Li J; Anhui Provincial Engineering Research Center for Polysaccharide Drugs, Anhui Province Key Laboratory of Active Biological Macro-Molecules, Department of Pharmacy, Wannan Medical College, Wuhu, 241000, China; Department of Pharmacy, Lu'an Affiliated Hospital of Anhui Medical University, Lu'an, 237000
Qian W; Anhui Provincial Engineering Research Center for Polysaccharide Drugs, Anhui Province Key Laboratory of Active Biological Macro-Molecules, Department of Pharmacy, Wannan Medical College, Wuhu, 241000, China.
Xu Y; Anhui Provincial Engineering Research Center for Polysaccharide Drugs, Anhui Province Key Laboratory of Active Biological Macro-Molecules, Department of Pharmacy, Wannan Medical College, Wuhu, 241000, China.
Chen G; School of Life Science and National Glycoengineering Research Center, Shandong University, Jinan, 250100, China.
Wang G; Anhui Provincial Engineering Research Center for Polysaccharide Drugs, Anhui Province Key Laboratory of Active Biological Macro-Molecules, Department of Pharmacy, Wannan Medical College, Wuhu, 241000, China.
Nie S; Department of Pharmacy, Lu'an Affiliated Hospital of Anhui Medical University, Lu'an, 237000, China.
Shen B; Department of Pharmacy, Lu'an Affiliated Hospital of Anhui Medical University, Lu'an, 237000, China.
Zhao Z; Anhui Provincial Engineering Research Center for Polysaccharide Drugs, Anhui Province Key Laboratory of Active Biological Macro-Molecules, Department of Pharmacy, Wannan Medical College, Wuhu, 241000, China.
Liu C; Anhui Provincial Engineering Research Center for Polysaccharide Drugs, Anhui Province Key Laboratory of Active Biological Macro-Molecules, Department of Pharmacy, Wannan Medical College, Wuhu, 241000, China.
Chen K; Anhui Provincial Engineering Research Center for Polysaccharide Drugs, Anhui Province Key Laboratory of Active Biological Macro-Molecules, Department of Pharmacy, Wannan Medical College, Wuhu, 241000, China; School of Life Science and National Glycoengineering Research Center, Shandong University, J

Carbohydr Polym ; 130: 97-103, 2015 Oct 05.

Article em En | MEDLINE | ID: mdl-26076605

Assuntos

Ativação de Macrófagos/efeitos dos fármacos; Polissacarídeos Bacterianos/isolamento & purificação; Polissacarídeos Bacterianos/farmacologia; Pseudoalteromonas/química; Animais; Regiões Antárticas; Sobrevivência Celular/efeitos dos fármacos; Camundongos; NF-kappa B/metabolismo; Óxido Nítrico/metabolismo; Fagocitose/efeitos dos fármacos; Fosforilação/efeitos dos fármacos; Transporte Proteico/efeitos dos fármacos; Células RAW 264.7/efeitos dos fármacos; Células RAW 264.7/metabolismo; Transdução de Sinais/efeitos dos fármacos; Fator de Necrose Tumoral alfa/metabolismo; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

Antarctic bacterium Pseudoaltermonas sp. S-5; Extracellular polysaccharide; Immunostimulatory activity; Nuclear factor-κB; p38 MAPK

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissacarídeos Bacterianos / Pseudoalteromonas / Ativação de Macrófagos Limite: Animals Idioma: En Revista: Carbohydr Polym Ano de publicação: 2015 Tipo de documento: Article

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