Technical prerequisites and imaging protocols for CT perfusion imaging in oncology.
Eur J Radiol
; 84(12): 2359-67, 2015 Dec.
Article
em En
| MEDLINE
| ID: mdl-26137905
ABSTRACT
The aim of this review article is to define the technical prerequisites of modern state-of-the-art CT perfusion imaging in oncology at reasonable dose levels. The focus is mainly on abdominal and thoracic tumor imaging, as they pose the largest challenges with respect to attenuation and patient motion. We will show that low kV dynamic scanning in conjunction with detection technology optimized for low photon fluxes has the highest impact on reducing dose independently of other choices made in the protocol selection. We discuss, derived from relatively simple first principles, on what appropriate temporal sampling and total scan duration depend on and why optimized contrast medium injection protocols are also essential in limiting dose. Finally we will examine the possibility of simultaneously extracting standard morphological and functional information from one single 4D examination as a potential enabler for a more widespread use of dynamic contrast enhanced CT in oncology.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Intensificação de Imagem Radiográfica
/
Tomografia Computadorizada por Raios X
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Meios de Contraste
Limite:
Humans
Idioma:
En
Revista:
Eur J Radiol
Ano de publicação:
2015
Tipo de documento:
Article
País de afiliação:
Alemanha