[Analysis of severe Legionellosis hospitalized in intensive care units in Tunisia]. / Analyse des cas de légionellose grave hospitalisés dans les services de réanimation en Tunisie.
Bull Soc Pathol Exot
; 108(3): 191-6, 2015 Aug.
Article
em Fr
| MEDLINE
| ID: mdl-26141497
ABSTRACT
This study is the first one that describes the situation of Legionnaires' disease (LD) in Tunisia, with its clinical and epidemiological characteristics and investigates the risk factors associated with Legionella infections in our country. We conducted a retrospective multicentric study during 5 years (2008-2012) concerning all confirmed LD cases in Tunisia and we investigated risk factors for infection. The total of confirmed LD cases was 14. Incidence was 0.03. Mean age 53.1, sex ratio (M/F) 2.6. Summer-autumnal peak was noted. Risk factors for infection were the great humidity at home (n=4), living in community (n=3) and practice ablutions (before prayer) in public places (n=4). Community acquired legionellosis (n=9) and nosocomial (n=2). Pulmonary symptoms (n=11)+/-gastrointestinal (n=6) and/or neurological signs (n=4). Beta lactams therapy failed (n=11). CXR showed bilateral lesions (n=6). Abnormalities in laboratory values were noted hyponatremia (n=9), high CPK levels (n=9). Diagnosis was confirmed by positive urinary Legionella antigens test (n=10) and by direct immunofluorescence (n=1). Treatment was based on bitherapy (n=10). Five patients died. The incidence of LD appears lower than other countries. Some risk factors, as ablutions, are different from that reported in Western countries and seem to be specific to our society. Given the seriousness of its consequences, it is strongly recommended to improve the national surveillance system up and register LD as notifiable disease.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Doença dos Legionários
/
Unidades de Terapia Intensiva
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
Limite:
Aged
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Female
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Humans
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Male
/
Middle aged
País/Região como assunto:
Africa
Idioma:
Fr
Revista:
Bull Soc Pathol Exot
Ano de publicação:
2015
Tipo de documento:
Article
País de publicação:
FR
/
FRANCE
/
FRANCIA
/
FRANÇA