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Comparative Analysis of Whole-Genome Sequences of Influenza A(H1N1)pdm09 Viruses Isolated from Hospitalized and Nonhospitalized Patients Identifies Missense Mutations That Might Be Associated with Patient Hospital Admissions in Finland during 2009 to 2014.
Mishel, Polina; Ojala, Teija; Benner, Christian; Lakspere, Triin; Bychkov, Dmitrii; Jalovaara, Petri; Kakkola, Laura; Kallio-Kokko, Hannimari; Kantele, Anu; Kankainen, Matti; Ikonen, Niina; Ripatti, Samuli; Julkunen, Ilkka; Kainov, Denis E.
Afiliação
  • Mishel P; The Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Ojala T; Institute of Biomedicine, Pharmacology, University of Helsinki, Helsinki, Finland.
  • Benner C; The Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Lakspere T; The Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Bychkov D; The Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Jalovaara P; The Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Kakkola L; Department of Virology, University of Turku, Turku, Finland.
  • Kallio-Kokko H; Helsinki University Hospital Laboratory (HUSLAB), Helsinki, Finland.
  • Kantele A; Department of Medicine, University of Helsinki, Helsinki, Finland Inflammation Center, Helsinki University Hospital, Helsinki, Finland.
  • Kankainen M; The Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.
  • Ikonen N; National Institute for Health and Welfare (THL), Helsinki, Finland.
  • Ripatti S; The Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland Department of Public Health, University of Helsinki, Helsinki, Finland Wellcome Trust Sanger Institute, Cambridge, United Kingdom.
  • Julkunen I; Department of Virology, University of Turku, Turku, Finland.
  • Kainov DE; The Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland denis.kainov@helsinki.fi.
Genome Announc ; 3(4)2015 Jul 30.
Article em En | MEDLINE | ID: mdl-26227588
Here, we report 40 new whole-genome sequences of influenza A(H1N1)pdm09 viruses isolated from Finnish patients during 2009 to 2014. A preliminary analysis of these and 186 other whole genomes of influenza A(H1N1)pdm09 viruses isolated from hospitalized and nonhospitalized patients during 2009 to 2014 in Finland revealed several viral mutations that might be associated with patient hospitalizations.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Genome Announc Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Finlândia País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Genome Announc Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Finlândia País de publicação: Estados Unidos