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A HER2-specific Modified Fc Fragment (Fcab) Induces Antitumor Effects Through Degradation of HER2 and Apoptosis.
Leung, Kin-Mei; Batey, Sarah; Rowlands, Robert; Isaac, Samine J; Jones, Phil; Drewett, Victoria; Carvalho, Joana; Gaspar, Miguel; Weller, Sarah; Medcalf, Melanie; Wydro, Mateusz M; Pegram, Robert; Mudde, Geert C; Bauer, Anton; Moulder, Kevin; Woisetschläger, Max; Tuna, Mihriban; Haurum, John S; Sun, Haijun.
Afiliação
  • Leung KM; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Batey S; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK. Electronic address: sarah.batey@f-star.com.
  • Rowlands R; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Isaac SJ; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Jones P; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Drewett V; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Carvalho J; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Gaspar M; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Weller S; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Medcalf M; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Wydro MM; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Pegram R; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Mudde GC; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Bauer A; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Moulder K; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Woisetschläger M; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Tuna M; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Haurum JS; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
  • Sun H; F-star Biotechnology Ltd, Babraham Research Campus, Cambridge, UK.
Mol Ther ; 23(11): 1722-1733, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26234505
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos Fc das Imunoglobulinas / Apoptose / Receptor ErbB-2 / Neoplasias Limite: Animals / Humans Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
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Imprimir
XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos Fc das Imunoglobulinas / Apoptose / Receptor ErbB-2 / Neoplasias Limite: Animals / Humans Idioma: En Revista: Mol Ther Assunto da revista: BIOLOGIA MOLECULAR / TERAPEUTICA Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos