Bortezomib Amplifies Effect on Intracellular Proteasomes by Changing Proteasome Structure.

Pitcher, David S; de Mattos-Shipley, Kate; Tzortzis, Konstantinos; Auner, Holger W; Karadimitris, Anastasios; Kleijnen, Maurits F

Pitcher, David S; de Mattos-Shipley, Kate; Tzortzis, Konstantinos; Auner, Holger W; Karadimitris, Anastasios; Kleijnen, Maurits F.

Afiliação

Pitcher DS; Centre for Haematology, Division of Experimental Medicine, Faculty of Medicine, Imperial College London, Hammersmith Campus, Commonwealth Building 4th Floor, Du Cane Road, London W12 0NN, United Kingdom.
de Mattos-Shipley K; Centre for Haematology, Division of Experimental Medicine, Faculty of Medicine, Imperial College London, Hammersmith Campus, Commonwealth Building 4th Floor, Du Cane Road, London W12 0NN, United Kingdom.
Tzortzis K; Centre for Haematology, Division of Experimental Medicine, Faculty of Medicine, Imperial College London, Hammersmith Campus, Commonwealth Building 4th Floor, Du Cane Road, London W12 0NN, United Kingdom.
Auner HW; Centre for Haematology, Division of Experimental Medicine, Faculty of Medicine, Imperial College London, Hammersmith Campus, Commonwealth Building 4th Floor, Du Cane Road, London W12 0NN, United Kingdom.
Karadimitris A; Centre for Haematology, Division of Experimental Medicine, Faculty of Medicine, Imperial College London, Hammersmith Campus, Commonwealth Building 4th Floor, Du Cane Road, London W12 0NN, United Kingdom.
Kleijnen MF; Centre for Haematology, Division of Experimental Medicine, Faculty of Medicine, Imperial College London, Hammersmith Campus, Commonwealth Building 4th Floor, Du Cane Road, London W12 0NN, United Kingdom.

EBioMedicine ; 2(7): 642-8, 2015 Jul.

Article em En | MEDLINE | ID: mdl-26288836

Assuntos

Bortezomib/farmacologia; Espaço Intracelular/enzimologia; Complexo de Endopeptidases do Proteassoma/química; Complexo de Endopeptidases do Proteassoma/metabolismo; Domínio Catalítico; Linhagem Celular Tumoral; Humanos; Mieloma Múltiplo/patologia

Palavras-chave

Bortezomib; CTAB-PAGE; Multiple myeloma; Posttranslational modification; Proteasome

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espaço Intracelular / Complexo de Endopeptidases do Proteassoma / Bortezomib Limite: Humans Idioma: En Revista: EBioMedicine Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Holanda

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