The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells.

Smirnova, Natalia F; Fontaine, Coralie; Buscato, Mélissa; Lupieri, Adrien; Vinel, Alexia; Valera, Marie-Cécile; Guillaume, Maeva; Malet, Nicole; Foidart, Jean-Michel; Raymond-Letron, Isabelle; Lenfant, Francoise; Gourdy, Pierre; Katzenellenbogen, Benita S; Katzenellenbogen, John A; Laffargue, Muriel; Arnal, Jean-Francois

Smirnova, Natalia F; Fontaine, Coralie; Buscato, Mélissa; Lupieri, Adrien; Vinel, Alexia; Valera, Marie-Cécile; Guillaume, Maeva; Malet, Nicole; Foidart, Jean-Michel; Raymond-Letron, Isabelle; Lenfant, Francoise; Gourdy, Pierre; Katzenellenbogen, Benita S; Katzenellenbogen, John A; Laffargue, Muriel; Arnal, Jean-Francois.

Afiliação

Smirnova NF; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Fontaine C; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Buscato M; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Lupieri A; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Vinel A; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Valera MC; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Guillaume M; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Malet N; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Foidart JM; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Raymond-Letron I; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Lenfant F; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Gourdy P; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Katzenellenbogen BS; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Katzenellenbogen JA; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Laffargue M; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B
Arnal JF; From the Department of Vascular Biology of the Institute of Metabolic and Cardiovascular Diseases (I2MC), Université de Toulouse 3, Institut National de la Santé et de la Recherche Médicale (INSERM) UMR1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (N.F.S., C.F., M.B

Circ Res ; 117(9): 770-8, 2015 Oct 09.

Article em En | MEDLINE | ID: mdl-26316608

Assuntos

Artérias/metabolismo; Receptor alfa de Estrogênio/metabolismo; Miócitos de Músculo Liso/metabolismo; Neointima/metabolismo; Actinas/metabolismo; Animais; Artérias/efeitos dos fármacos; Artérias/patologia; Membrana Celular/metabolismo; Núcleo Celular/metabolismo; Proliferação de Células/efeitos dos fármacos; Endotélio Vascular/efeitos dos fármacos; Endotélio Vascular/metabolismo; Endotélio Vascular/patologia; Estradiol/farmacologia; Receptor alfa de Estrogênio/genética; Estrogênios/farmacologia; Artéria Femoral/efeitos dos fármacos; Artéria Femoral/lesões; Artéria Femoral/metabolismo; Hiperplasia; Imuno-Histoquímica; Camundongos Endogâmicos C57BL; Camundongos Knockout; Camundongos Transgênicos; Músculo Liso Vascular/efeitos dos fármacos; Músculo Liso Vascular/metabolismo; Músculo Liso Vascular/patologia; Miócitos de Músculo Liso/efeitos dos fármacos; Neointima/genética; Ovariectomia; Molécula-1 de Adesão Celular Endotelial a Plaquetas/metabolismo; Túnica Íntima/efeitos dos fármacos; Túnica Íntima/metabolismo

Palavras-chave

estradiol; estrogen receptor alpha; mice; myocytes; smooth muscle

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artérias / Miócitos de Músculo Liso / Receptor alfa de Estrogênio / Neointima Limite: Animals Idioma: En Revista: Circ Res Ano de publicação: 2015 Tipo de documento: Article País de publicação: Estados Unidos

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