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Nasal irrigation: From empiricism to evidence-based medicine. A review.
Bastier, P-L; Lechot, A; Bordenave, L; Durand, M; de Gabory, L.
Afiliação
  • Bastier PL; Service d'ORL et de chirurgie cervico-faciale, centre Michelet, hôpital Pellegrin, CHU de Bordeaux, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
  • Lechot A; Service d'ORL et de chirurgie cervico-faciale, centre Michelet, hôpital Pellegrin, CHU de Bordeaux, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France.
  • Bordenave L; U1026, bio-ingénierie tissulaire, université de Bordeaux, 33000 Bordeaux, France; CIC-IT, CHU de Bordeaux, 33000 Bordeaux, France.
  • Durand M; CIC-IT, CHU de Bordeaux, 33000 Bordeaux, France.
  • de Gabory L; Service d'ORL et de chirurgie cervico-faciale, centre Michelet, hôpital Pellegrin, CHU de Bordeaux, place Amélie-Raba-Léon, 33076 Bordeaux cedex, France; CIC-IT, CHU de Bordeaux, 33000 Bordeaux, France. Electronic address: ludovic.de-gabory@chu-bordeaux.fr.
Eur Ann Otorhinolaryngol Head Neck Dis ; 132(5): 281-5, 2015 Nov.
Article em En | MEDLINE | ID: mdl-26344138
Nasal irrigation plays a non-negligible role in the treatment of numerous sinonasal pathologies and postoperative care. There is, however, a wide variety of protocols. The present review of the evidence-based literature sought objective arguments for optimization and efficacy. It emerged that large-volume low-pressure nasal douche optimizes the distribution and cleansing power of the irrigation solution in the nasal cavity. Ionic composition and pH also influence mucociliary clearance and epithelium trophicity. Seawater is less rich in sodium ions and richer in bicarbonates, potassium, calcium and magnesium than is isotonic normal saline, while alkaline pH and elevated calcium concentration optimized ciliary motility in vitro. Bicarbonates reduce secretion viscosity. Potassium and magnesium promote healing and limit local inflammation. These results show that the efficacy of nasal irrigation is multifactorial. Large-volume low-pressure nasal irrigation using undiluted seawater seems, in the present state of knowledge, to be the most effective protocol.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lavagem Nasal Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Eur Ann Otorhinolaryngol Head Neck Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: França País de publicação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Lavagem Nasal Tipo de estudo: Guideline Limite: Humans Idioma: En Revista: Eur Ann Otorhinolaryngol Head Neck Dis Ano de publicação: 2015 Tipo de documento: Article País de afiliação: França País de publicação: França