Highly sensitive electrochemical sensor based on ß-cyclodextrin-gold@3, 4, 9, 10-perylene tetracarboxylic acid functionalized single-walled carbon nanohorns for simultaneous determination of myricetin and rutin.
Anal Chim Acta
; 892: 85-94, 2015 Sep 10.
Article
em En
| MEDLINE
| ID: mdl-26388478
ABSTRACT
The application of macrocyclic hosts for construction of different electrochemical devices and separation matrices has attracted much attentions due to their benign biocompatibility and simplicity of synthesis. Myricetin and rutin are considered two of the most bioactive flavonoids, which have been proved to exhibit various physiological functions. This work reports a simple and facile approach for the synthesis of ß-cyclodextrin-gold@3, 4, 9, 10-perylene tetracarboxylic acid functionalized single-walled carbon nanohorns (ß-CD-Au@PTCA-SWCNHs) nanohybrids. The simultaneous electrochemical determination of myricetin and rutin using a ß-CD-Au@PTCA-SWCNHs-modified glassy carbon electrode was established. The results show that the ß-CD-Au@PTCA-SWCNHs-modified electrode displayed electrochemical signal superior to those of Au@PTCA-;SWCNHs and SWCNHs towards myricetin and rutin. The proposed modified electrode has a linear response range of 0.01-10.00 µM both for myricetin and rutin with relatively low detection limits of 0.0038 µM for myricetin and 0.0044 µM (S/N = 3) for rutin, respectively. The excellent performance of the sensing platform is considered to be the synergic effects of the SWCNHs (e.g. their good electrochemical properties and large surface area) and ß-CD (e.g. a hydrophilic external surface, a high supramolecular recognition, and a good enrichment capability).
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Perileno
/
Rutina
/
Flavonoides
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Nanotubos de Carbono
/
Técnicas Eletroquímicas
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Anal Chim Acta
Ano de publicação:
2015
Tipo de documento:
Article