Essential Role of the EF-hand Domain in Targeting Sperm Phospholipase CÎ¶ to Membrane Phosphatidylinositol 4,5-Bisphosphate (PIP2).

Nomikos, Michail; Sanders, Jessica R; Parthimos, Dimitris; Buntwal, Luke; Calver, Brian L; Stamatiadis, Panagiotis; Smith, Adrian; Clue, Matthew; Sideratou, Zili; Swann, Karl; Lai, F Anthony

Nomikos, Michail; Sanders, Jessica R; Parthimos, Dimitris; Buntwal, Luke; Calver, Brian L; Stamatiadis, Panagiotis; Smith, Adrian; Clue, Matthew; Sideratou, Zili; Swann, Karl; Lai, F Anthony.

Afiliação

Nomikos M; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and mixosn@yahoo.com.
Sanders JR; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and.
Parthimos D; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and.
Buntwal L; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and.
Calver BL; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and.
Stamatiadis P; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and.
Smith A; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and.
Clue M; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and.
Sideratou Z; the National Center for Scientific Research "Demokritos," 15310 Aghia Paraskevi, Greece.
Swann K; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and.
Lai FA; From the Institute of Molecular and Experimental Medicine, School of Medicine, Cardiff University, Cardiff CF14 4XN, United Kingdom and lait@cf.ac.uk.

J Biol Chem ; 290(49): 29519-30, 2015 Dec 04.

Article em En | MEDLINE | ID: mdl-26429913

Assuntos

Membrana Celular/metabolismo; Motivos EF Hand; Fosfatidilinositol 4,5-Difosfato/metabolismo; Fosfoinositídeo Fosfolipase C/metabolismo; Espermatozoides/enzimologia; Animais; Cálcio/metabolismo; Sinalização do Cálcio; Cátions; Feminino; Hidrólise; Lipossomos/química; Masculino; Camundongos; Modelos Teóricos; Mutação; Oócitos/citologia; Ácidos Fosfatídicos/metabolismo; Fosfatidilserinas/metabolismo; Plasmídeos/metabolismo; Ligação Proteica

Palavras-chave

EF-hand domain; PIP2; calcium intracellular release; fertilization; inositol 1,4,5-trisphosphate; phosphatidylinositol signaling; phospholipase C; sperm

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Espermatozoides / Membrana Celular / Fosfatidilinositol 4,5-Difosfato / Motivos EF Hand / Fosfoinositídeo Fosfolipase C Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2015 Tipo de documento: Article País de publicação: Estados Unidos

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