Chronic Influences of Obstructive Sleep Apnea on Cerebral Venous Flow.
J Ultrasound Med
; 34(11): 2043-8, 2015 Nov.
Article
em En
| MEDLINE
| ID: mdl-26432825
ABSTRACT
OBJECTIVES:
Evidence reveals a pathophysiologic link between sleep apnea syndrome and cerebrovascular diseases. It is known that obstructive sleep apnea (OSA) may cause serial hemodynamic changes and structural abnormalities in the cerebral and cardiac arterial systems, but its effect on the cerebral venous system has remained unclear. The purpose of this study was to compare internal jugular vein hemodynamics between patients with OSA and healthy individuals.METHODS:
Patients with OSA and age-, body mass index-, and sex-matched healthy control participants were recruited for a jugular venous duplex study and neurologic examination. The luminal area of the internal jugular vein, jugular venous flow volume, time-averaged mean velocity, and presence of jugular venous reflux were recorded. These flow characteristics were obtained at different respiratory statuses, and we analyzed the differences between patients and controls.RESULTS:
In the OSA group, there was an increasing flow volume in total internal jugular veins at rest. The frequency of venous reflux in patients compared with controls was significantly decreased (26.7% versus 53.3%, respectively; P < .05). The internal jugular vein drainage dominance was greater on the left side in the OSA group (right versus left 48.8% versus 51.2%), whereas it was greater on the right side in the control group (right versus left 61.7% versus 38.3%).CONCLUSIONS:
Our data showed peculiar internal jugular vein hemodynamics at baseline and different respiratory statuses in patients with OSA. These characteristics imply that cerebral venous drainage conditions might be involved in the pathophysiologic mechanisms of OSA syndrome.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Velocidade do Fluxo Sanguíneo
/
Veias Cerebrais
/
Circulação Cerebrovascular
/
Apneia Obstrutiva do Sono
/
Veias Jugulares
Tipo de estudo:
Diagnostic_studies
Limite:
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
J Ultrasound Med
Ano de publicação:
2015
Tipo de documento:
Article