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[Prevalence of non-alcoholic fatty liver disease in a population with elevated transaminases and level of accuracy of the diagnosis in Primary Care]. / Prevalencia de la esteatosis hepática no alcohólica en población con hipertransaminasemia y grado de adecuación del diagnóstico registrado en atención primaria.
Samperio-González, María Amelia; Selvi-Blasco, Marta; Manzano-Montero, Mónica; Méndez-Gómez, Judit; Gil-Prades, Montserrat; Azagra, Rafael.
Afiliação
  • Samperio-González MA; Centro de Atención Primaria Horta 7F, Institut Català de la Salut, Barcelona, España.
  • Selvi-Blasco M; Centro de Atención Primaria Horta 7D, Institut Català de la Salut, Barcelona, España.
  • Manzano-Montero M; Centro de Atención Primaria Horta 7F, Institut Català de la Salut, Barcelona, España.
  • Méndez-Gómez J; Centro de Atención Primaria Horta 7F, Institut Català de la Salut, Barcelona, España.
  • Gil-Prades M; Hospital de Sabadell, Corporació Sanitaria Parc Taulí, Sabadell, Barcelona, España.
  • Azagra R; Centro de Atención Primaria Badia del Vallès, Institut Català de la Salut, GROIMAP de USR MN-IDIAP Jordi Gol, Universitat Autònoma de Barcelona, Barcelona, España. Electronic address: rafael.azagra@uab.cat.
Aten Primaria ; 48(5): 281-7, 2016 May.
Article em Es | MEDLINE | ID: mdl-26441288
UNLABELLED: Nonalcoholic fatty liver disease (NAFLD) is the most common cause of elevated transaminases in adults. AIM: Determine the prevalence of NASH in patients with sustained hypertransaminasemia, and Know the adequacy of the registered in Primary Care (AP) diagnosis. MATERIAL AND METHODS: 1) Cross-sectional study with a random sample of patients with elevated alanine aminotransferase (ALT) held (ALT> 32 for ≥6 months), ruling out other causes of liver disease, according to clinical, laboratory and ultrasound scan criteria in AP and 2) cross-sectional description of all cases diagnosed with NASH recorded (K76 - ICD10) with diagnostic adequacy analysis according to standard criteria. RESULTS: 290 patients were analyzed: 76 were diagnosed as NASH (26.1%), 44 women (57.9%). Multivariate analysis adjusted for age and sex showed no association between NASH and male gender (OR: 0.5; CI95%: 0.3-0.9), diabetes mellitus (DM) (OR: 2.42; CI95%: 1.2-4.9) and hypertension blood pressure (HBP) (OR: 3.07; CI 95% 1.6-5.6). Of the 209 diagnosed with NASH record: 51 (24.4%) met the criteria for NASH. The rest had insufficient records. HIGHLIGHTS: 53.1% lacked sustained hypertransaminasemia; 48% of viral serology; 11% supported and 53.1% abdominal ultrasound registration of alcohol. CONCLUSIONS: Severe NASH is frequent among patients with sustained hypertransaminasemia. The DM and hypertension significantly increase the risk of NASH. The diagnosis of NASH is recorded without considering all criteria and mainly NASH made by ultrasonography. They should unify diagnostic criteria in the register of NASH.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atenção Primária à Saúde / Alanina Transaminase / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Female / Humans / Male / Middle aged Idioma: Es Revista: Aten Primaria Ano de publicação: 2016 Tipo de documento: Article País de publicação: Espanha

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Atenção Primária à Saúde / Alanina Transaminase / Hepatopatia Gordurosa não Alcoólica Tipo de estudo: Diagnostic_studies / Observational_studies / Prevalence_studies / Risk_factors_studies / Screening_studies Limite: Female / Humans / Male / Middle aged Idioma: Es Revista: Aten Primaria Ano de publicação: 2016 Tipo de documento: Article País de publicação: Espanha