PIMASERTIB AND SEROUS RETINAL DETACHMENTS.
Retin Cases Brief Rep
; 10(2): 191-6, 2016.
Article
em En
| MEDLINE
| ID: mdl-26444523
PURPOSE: To report a case of multifocal serous retinal detachments associated with pimasertib. METHODS: The authors report a 26-year-old patient who developed bilateral multifocal serous retinal detachments appearing 2 days after starting pimasertib (as part of a clinical trial investigating its use in low-grade metastatic ovarian cancer) and rapidly resolving 3 days after stopping it. CONCLUSION: The mechanism of MEK inhibitor induced visual toxicity remains unclear. The pathophysiology of multifocal serous retinal detachments as a complication of pimasertib is still poorly understood.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Retina
/
Descolamento Retiniano
/
Niacinamida
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
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Humans
Idioma:
En
Revista:
Retin Cases Brief Rep
Ano de publicação:
2016
Tipo de documento:
Article
País de afiliação:
Canadá
País de publicação:
Estados Unidos